Prototype 2 takes place in New York City and features super-powers, so where better than New York Comic-Con to show off the latest trailer? The latest look at the game shows the protagonist Heller beating down some fools in his search for Mercer, the anti-hero of the last game. His personal stake involves a dead wife and daughter, and as comics like The Punisher have taught us, revenge can be a powerful motivator.

This particular trailer features a little twist on the formula, as Heller seems to command the monsters. We would bet that's a gameplay mechanic just waiting to be detailed by developer Radical Entertainment. The game is set for April 24, 2012.