While much of this has been known for years, the Blizzard post does offer some insight into how boss encounters may work given the game's reduced focus on quaffing sweet potions.

Major boss fights make unique use of health globes. Each boss battle includes a custom-designed means of utilizing these globes to regain health. For example, in one fight, you might have to split your attention between weakening a dangerous boss and slaying its irritating but ultimately less-dangerous minions in order to get enough health globes to stay standing. In another fight, the boss itself might drop health globes when it takes damage, or you might have to hunt for hidden caches of globes in the midst of battle.

It sounds like Blizzard is incorporating experience gained in designing boss encounters in World of Warcraft into Diablo III. If so, it's likely to be a divisive issue in the community. I, for one, welcome more complex encounters that don't boil down to kiting and abusing town portals.