The 3D version features the arcade release's gameplay, with a new audio-visual overhaul. The unlucky souls of the planet Zardon still need help defending against an ever-increasing onslaught of Krytolian missiles. One or two sharpshooters, sans trackballs, can play locally or over Xbox Live.

This release won't be the first 3D Missile Command. Virtuality Entertainment released Missile Command 3D, a first-person update to the classic, for the ill-fated Atari Jaguar in 1995.