"We are taking a break from the Metroid series and from Samus," said Pacini in a Yahoo! Games video interview. "So I'm sure there will be other titles created, but as far as Retro Studios is concerned, we're taking a break for a little bit."

As Nintendo's premier Western development studio, it is very likely Retro has other Wii projects in the works, though none are announced. Before shaving down development to focus on the original Metroid Prime (GCN), released in 2002, Retro was working on numerous projects including the widely-known RPG Raven Blade. It is unknown if Retro will resurrect any defunct properties.

Pacini also spoke on the challenges of properly using the system's unique controller. "We spent a great deal of time and research on how the controls should work and what people actually do when they play these games," he said. "I think that all too often with the initial games on the Wii, the thought was, 'Let's do as many interesting things as we can with the controller,' even though they might not have a direct connection to what the player's doing, and that often comes off as feeling kind of contrived or, 'Man, the Wii controller doesn't work that well.'

"But what we tried to do with Metroid Prime 3 and what we as developers will continue to do, and other developers, is think of things, ideas and mechanics that make the player feel that there's a relationship between what I'm doing in my hand and what's being related on screen."